منابع مشابه
Klotho Protein,A Biomarker for AKI
Klotho is an anti-aging single-pass membrane protein that is mainly produced in the kidney. The level of soluble klotho decreases with age and the klotho gene is associated with an increased risk of age-related diseases, such as diabetes, skin atrophy, chronic kidney disease, ataxia and cancer. The klotho gene is composed of five exons and encodes a membrane glycoprotein located in the plasma ...
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Predicting Protein Molecular Function by Barbara Elizabeth Engelhardt Doctor of Philosophy in Computer Science and the Designated Emphases in Computational and Genomic Biology and Communication, Computation, and Statistics University of California, Berkeley Professor Michael I. Jordan, Chair The number of known nucleotide sequences encoding proteins is growing at an extraordinarily fast rate du...
متن کاملKlotho as a Novel Cardioprotective Protein in Aged Heart
In recent years, researchers have been looking for genes whose products can directly affect the aging process. Among these, the anti-aging protein klotho has attracted much attention. This single transmembrane protein is expressed in the renal tissues, parathyroid gland and choroid network of the brain and acts as a co-receptor for Fibroblast Growth Factor FGF. In this way, it contributes to c...
متن کاملBiological Role of Anti-aging Protein Klotho
Klotho-deficient mice have accelerated aging phenotypes, whereas overexpression of Klotho in mice extends lifespan. Klotho is an anti-aging single-pass membrane protein predominantly produced in the kidney, with shedding of the amino-terminal extracellular domain into the systemic circulation. Circulating levels of soluble Klotho decrease with age, and the klotho gene is associated with increas...
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translation as a comunicative process is always said to be associated with various aspects of meaning loss or gain. subtitling as a mode of translating, due to special discoursal and textual conditions imposed upon it, is believed to be an obvious case of this loss or gain. presenting the spoken sound track of a film in writing and synchronizing the perception of this text by the viewers with...
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ژورنال
عنوان ژورنال: Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
سال: 2003
ISSN: 0300-9173
DOI: 10.3143/geriatrics.40.452